Patrick Chen

Vice President, CMC & Technical Operations

Mr. Chen joined Senti Bio in 2023 and leads the CMC / Technical Operations department and is responsible for the process development, analytical development, and manufacturing activities.  He brings over 30 years of experience in the biopharma industry in the development and manufacturing of proteins, enzymes, monoclonal antibodies, gene and cell therapy products.  Prior to Senti Bio, Mr. Chen was Vice President of Manufacturing at Grace Science and led the CMC activities for the development and manufacturing of a gene therapy for an ultra rare disease indication. Prior to that, he was the head of External Manufacturing at Sangamo Therapeutics and was responsible for GMP manufacturing and supply of plasmids, mRNA, viral vectors and cell therapy products including stem cells and Treg cells. Mr. Chen has had increasing roles of responsibility and has been in involved in the initial process development and manufacturing of Humira®, the design of a large-scale biologics manufacturing facility for Amgen Rhode Island to manufacture Enbrel®, led the CMC project management department at Chiron and was the CMC and tech transfer leader at Genentech for various products including Activase®, Rituxan® and Perjeta®.

Mr. Chen received his Chemical Engineering degree from UCLA and his MBA from the Babson FW Olin Graduate School of Business.